What's New

version 0.8.7.0 (2026-05-09)

This release adds a new Mixed Models for Repeated Measures (MMRM) procedure for longitudinal and repeated-measures analyses with incomplete follow-up data. The implementation supports REML/ML estimation, flexible within-subject covariance structures, Kenward-Roger, Satterthwaite, between-within, residual, and large-sample inference options, Type III tests, LS-means, pairwise contrasts, custom linear estimates through BESH.REGR.MMRM_LSMESTIMATE, fitted values, residuals, covariance diagnostics, and worksheet-function workflows. MMRM is available from the Regression ribbon and through the BESH.REGR.MMRM_* worksheet functions.
Added support for categorical-factor interactions in regression/GEE/MMRM model building and formula validation, enabling terms such as factor(A):B and factor(A):factor(B) for common MMRM use cases such as group-by-time effects.
New Interrupt buttons were added to the regression forms, allowing long-running calculations to stop at the next safe point and return the latest available estimates where supported. Closing a form during a run now requests a clean cancellation instead of leaving the calculation running
Multiple linear regression VIF output now includes a signed Partial r column for each modeled predictor column, computed from the coefficient t-statistic and residual degrees of freedom.

Added model-reporting tools for fitted binary classifiers, including confusion matrix, threshold-performance table, sensitivity/specificity and precision/recall summaries, calibration analysis, Brier score, ROC tables, and ROC plot outputs for binomial GLM and binomial GEE models. The same reporting workflow is also available through new generic classification UDFs for scoring external or holdout predictions directly in Excel.
Agreement-method bootstrap BCa intervals are now implemented in the backend for Lin's CCC, Cohen's / Weighted Kappa, Deming regression, and Bland–Altman analysis.
The Excel dialog for Cohen's / Weighted Kappa now exposes the backend jackknife confidence interval option.
Improved numerical accuracy of the linear regression estimation to pass NIST reference datasets results unittests.

Excel user defined functions exposed (5th batch including Agreement related functions for Bland-Altman analysis, Passing-Bablok, Deming regression, ICC, Lin's CCC, and Cohen's Kappa. Multivariate analysis UDFs - PCA, Factor analysis, K-means clustering, Hierarchical clustering, Correspondence and Multiple corespondence analysis)
fixed base URL for the UDFs help in the build in Excel formula windows form link
New Sample size calculation methods including UDFs
Addition of the Discriminant analysis including UDFs
New methods for testing non-inferiority and equivalence for the unpaired t-test, two independent proportions, and bland-altman agreement

Excel user defined functions exposed (4th batch including multiple linear regression model, generalized linear model, GLM NB2 with dispersion parameter estimation, Zero-Inflated Poisson regression, GEE)
Addition of new methods:
the Cluster analysis including K-means clustering, and Hierarchical clustering with dendrogram
Exploratory Factor analysis
Weighted Deming Regression
Weighted kappa
Lin CCC
Bland–Altman

Excel user defined functions exposed (3rd batch including ordinal and multinomial logistic regression functions, multiple comparison procedures for one-way ANOVA, one-way repeated measures ANOVA, Friedman test, and Kruskal–Wallis test, a set of assumption tests (normality, symmetry, etc.))
Existing COX fit excel user defined functions enhancement of "FORMULA=" parameter that supports categorical factors, polynomial terms, and continuous-variable interaction terms specifications.
GLM, NB2, ordinal logistic, and multinomial logistic Build Model tabs now support categorical factors, polynomial terms, and continuous-variable interaction terms.
GEE Build Model tab now supports categorical factors, polynomial terms, and continuous-variable interaction terms.
Zero-Inflated Poisson Build Model tabs now support categorical factors, polynomial terms, and continuous-variable interaction terms in both the Poisson and Logistic components.
Zero-Inflated Poisson now uses separate authored-effect lists and separate starting-value vectors for the Poisson and Logistic parts.
GLM-family, GEE, and ZIP regression pages now document expanded-design-matrix parameter counting for user-supplied starting values.
Bug fix in Kendall's tau-b confidence interval calculation.
Significance-level (alpha) option added to all applicable functions that returns confidence intervals.

Excel user defined functions exposed (2nd batch including COX proportional hazard model functions, ANOVA tables ...)
Multiple linear regression (linear model) now allows the categorical predictor to be specified as factor. The user does not need to create dummy variables in advance, and additionally the underlying class correctly handles the degrees of freedom in the ANOVA table.
XYZ scatter plot now allows the manual axis scaling. User interface was slightly modified based on addition of new user controls.
Internal dependency from NLOG package removed and in-house simple logger implemented. It resulted in about 20% size reduction of final addin .XLL file.

Excel user defined functions exposed (1st batch including some distribution CDFs, nonparametric tests, survival analysis related tests)
Auto update feature added
XYZ 3D scatterplot enhancements. Option added to flip each axis. Overlay 3D wire frames objects (sphere, ellipsoid).
bug fix with histogram normal curve overlay computation where with certain input data histogram bin midpoints coming into GaussOverlayComputation were wrong (rounded too aggressively), which then makes GaussOverlayComputation compute the wrong bin width and over-scaled the curve.

Chart exporting dialog added. It supports excel chart exporting in various image formats and image quality suitable for publications.
3D scatterplot chart now supports creation of animated GIF.
Multiple linear regression (linear model) now allows specification of polynomial and interaction terms.
Internal regression data input handling was refactored to enable future enhancements.

New agreement related methods added including Passing-Bablok and Deming Regression; Various versions of Intraclass correlation coefficients

(Bug fix) Fixed input table dimensions check in 2x2 table by-worksheet-input where (3 x 3 had been actually checked instead of 2 x 2 dimensions)
In all inputs containing built-in RefEdit control, the 1st control is selected on Windows form start